Executive summary

The Middle East and Africa encompass diverse regulatory systems with no single regional regime. The GCC Drug Registration system partially harmonises requirements among Gulf states. The African Medicines Agency (AMA) treaty entered into force in 2021 but operationalisation remains in progress as of 2026. Each country independently regulates peptide medicines, compounding, and research-use products.


Middle East

  • GCC (Gulf Cooperation Council): the GCC Drug Registration system provides a unified marketing authorisation pathway for Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the UAE. Individual states also have national procedures.

  • SFDA (Saudi Food and Drug Authority): separate national registration for Saudi Arabia, also participates in GCC system.

  • MOHAP / DHA / HAAD (UAE): federal and emirate-level authorities for medicines regulation.

  • Israel Ministry of Health — Pharmaceutical Administration: independent regulatory system.

Approved medicines

Some national registers include GLP-1 receptor agonists, insulin analogues, GnRH analogues, and somatostatin analogues. Availability and authorization are country- and product-specific; an FDA or EMA authorization does not itself authorize supply in a Middle Eastern jurisdiction.

Compounding

  • Saudi Arabia: SFDA authorises compounding for individual patient needs under specified conditions; bulk peptide raw materials from unregistered sources are not permitted.

  • UAE: Federal Decree-Law No. 38/2024 governs pharmacy practice including compounding. Prescription-based, patient-specific.

  • Israel: Pharmacists Regulations 1986 govern extemporaneous preparation. Unregistered bulk substances cannot be used.

  • These examples do not establish a region-wide rule. Whether an unapproved peptide may be used in compounding depends on the current national instrument, product, facility authorization, prescription, and import status.

Import

  • In the Middle Eastern jurisdictions reviewed, commercial import generally requires product authorization, subject to national exceptions. Personal import policies vary by country:

    • GCC states generally permit limited personal import of approved medicines with a prescription.

    • Israel Regulation 29 permits import of unapproved medicines for personal use under specific conditions (prescription, quantity limits).

  • Research peptides for institutional use may be imported with appropriate permits.

Research-use-only products

No general regional "research use only" exemption was identified. The legal effect of a disclaimer depends on national law and the product's composition, claims, intended use, recipient, and supply chain. This page does not establish the rule for every country.

Enforcement examples

  • National authorities publish enforcement notices concerning unauthorized medicines. Peptide-specific frequency or regional enforcement rates were not verified for this atlas; consult the named regulator's current notice archive.


Africa

  • AMA (African Medicines Agency): treaty entered into force 5 November 2021. As of August 2026, the Agency is being operationalised. It will eventually harmonise regulatory requirements but does not replace national authorities.

  • WHO Prequalification Programme: provides independent assessment of medicines for UN procurement; used as reference by many African regulators.

  • National authorities:

    • SAHPRA (South African Health Products Regulatory Authority).

    • NAFDAC (National Agency for Food and Drug Administration and Control, Nigeria).

    • PPB (Pharmacy and Poisons Board, Kenya).

    • FDA Ghana, MCC Zimbabwe, Tanzania FDA, Rwanda FDA, etc.

Approved medicines

Authorization pathways and reliance on reference agencies differ by country. Some national registers contain GLP-1 agonists and insulins, but no continent-wide product availability claim should be inferred.

Compounding

  • South Africa: Medicines Act s. 22C permits compounding per prescription. Manufacturing licence required for anything beyond extemporaneous scale.

  • Nigeria: PCN (Pharmacists Council of Nigeria) regulations govern compounding. Bulk unregistered APIs cannot be used.

  • Kenya: Pharmacy and Poisons Act governs compounding; similar constraints.

Import

  • In the African jurisdictions reviewed, commercial import generally requires product registration or a permit. Section 21 of the South African Medicines Act allows access to unapproved medicines for individual patients on application.

  • Nigeria: NAFDAC NCS (Notice of Confiscation and Seizure) applies to unauthorised imports.

  • Kenya: PPB controls import permits; unregistered peptides are seized.

Research-use-only products

No continent-wide exemption or prohibition can be inferred from a "research use only" label. National law, intended use, claims, importer status, and the facts of supply control. Country-specific legislation must be checked.

Enforcement examples

  • SAHPRA, NAFDAC, and other national authorities publish medicine-enforcement notices. This overview does not quantify peptide-specific actions or infer uniform online enforcement across countries.

Practical interpretation limits

This is general regulatory research, not legal advice. Classification can turn on composition, claims, intended use, route, supplier role, and facts not captured by a product name.

Primary sources