Approved regimen
Approved labeled regimen
Product-, indication-, and jurisdiction-specific — see the monograph
- CIC: 3 mg PO once daily with or without food. IBS-C: 3 mg PO once daily with or without food.
Dose evidence detail — Plecanatide
Detailed dose evidence documented for Plecanatide in its monograph — reference only, not dosing recommendations.
Reference only — not a dosing recommendation.
Studied in trials
Studied regimens (not recommendations)
Studied in trials — not a recommended dose
- 6 mg dose studied in phase 3 but did not provide additional efficacy.
- No other regimens studied in adequate trials.
Not established
What is not established
- Use in opioid-induced constipation.
- Efficacy <12 weeks not separately demonstrated.
- No established or recommended human dose for any other indication.
Plecanatide — secção de evidência de dose e administração da monografia