Detailed dose evidence documented for Cosyntropin in its monograph — reference only, not dosing recommendations.
Reference only — not a dosing recommendation.
Approved regimen
Approved labeled regimen
Product-, indication-, and jurisdiction-specific — see the monograph
Diagnostic use (US label): 0.25 mg (250 mcg) IV or IM, with cortisol sampling according to the labeled diagnostic protocol. Cortrosyn is supplied as a lyophilized prescription product; preparation must follow the exact current product label and the testing institution's protocol.
Studied in trials
Studied regimens (not recommendations)
Studied in trials — not a recommended dose
Low-dose SST: 1 mcg IV (proposed for mild secondary insufficiency; not standard).
Depot Synacthen (EU): 0.5–1 mg IM, used in some longer stimulation protocols.
Not established
What is not established
No established or recommended human dose for therapeutic uses (unless specifically indicated for infantile spasms under local protocols).