Detailed dose evidence documented for Dihexa in its monograph — reference only, not dosing recommendations.
Reference only — not a dosing recommendation.
Not established
No approved labeled regimen
No established or recommended human dose.
No established or recommended human dose.
Studied in trials
Studied regimens (not recommendations)
Studied in trials — not a recommended dose
The only published human PK data are for the prodrug fosgonimeton (SC 2–90 mg). No human data exist for Dihexa itself. Rodent studies used approximately 2 mg/kg oral.
Not established
What is not established
Any safe or effective human dose
Human pharmacokinetics (half-life, bioavailability, distribution, clearance)