Detailed dose evidence documented for Follistatin-344 in its monograph — reference only, not dosing recommendations.
Reference only — not a dosing recommendation.
Not established
No approved labeled regimen
No established or recommended human dose.
Not applicable.
Studied in trials
Studied regimens (not recommendations)
Studied in trials — not a recommended dose
No established or recommended human dose. Gene therapy doses in the BMD trial: 3×10¹¹ – 1.5×10¹² vg/kg, single intramuscular injection into quadriceps.
Not established
What is not established
No injectable follistatin peptide dose has been validated in humans
Gene therapy data cannot be extrapolated to protein/peptide injection
The half-life of recombinant follistatin protein in humans (~90 minutes) precludes practical systemic protein administration
Injectable "follistatin" products sold as research chemicals have no relationship to the gene therapy construct studied in clinical trials